ISSCR recommendations re. the use of isogenic iPSC lines for research
The recommendations contained within the ISSCR Standards relating to the need for the use of isogenic cell lines in iPSC research is driving demand for low cost, rapid production of high quality isogenic iPSC lines
The ISSCR Standards refer twice to isogenic cell lines
“Recommendation 4.4.1: consider variability when determining the necessary number of disease and control stem cell derivatives…”
“If replication is not possible, then variability should be reduced by using isogenic controls”
“Recommendation 4.4.4: when comparing isogenic cells derived from genome manipulation, multiple independent clones should be assessed.”
” ‘Independent lines’ are considered to mean derivatives of a single cell selected during reprogramming or gene modification (correction or mutation) arising in an independent well.”
“Production-engineered”, rapid, low-cost, fully- documented generation of high quality isogenic iPSC lines via the use of technology
There is increasing demand from iPSC researchers for the supply of high quality isogenic cell lines
Cost effectively. Rapidly. With full documentation.
Cellected has spent considerable time working on optimising every element of the work packages needed to produce isogenic iPSC cell lines to enable researchers to comply with the relevant the ISSCR recommendations.
The use of single cell cloning technology enables Cellected to provide clients with high quality isogenic iPSC lines at an attractive price
We think that you will be impressed by our isogenic iPSC service that can provide you with cost-effective, high quality isogenic iPSC lines that help researchers comply to the relevant ISSCR Standards’ recommendations.
