RIQUEST & RESCUE: solution for iPSC genetic integrity QC
Frequent testing and QC of iPSC lines – as mandated by the ISSCR Standards – should not be a cause for concern.
Cellected’s novel services enhance iPSC quality through monitoring and most importantly, recovering cells if there is a genomic abnormality or genetic heterogeneity. This is key for anyone working with iPSCs, be it multi-gene editing, drug discovery or organoid research.
RESCUE from Cellected
Cellected’s RESCUE service comprises 4 key elements – which are fully documented and have been designed mindful of the ISSCR Standards
cloning / seeding
The use of specialist, automated single cell cloning technology from Advanced Instruments enables the generation of large numbers of iPSC clones.
Growth & Morphology
The resultant iPSC clones are selected for optimal growth and morphology characteristics using proprietary AI-based analytics.
– in process QC
The selected iPSC clones are rapidly analysed and selected for quality and stability, per Cellected’s RIQUEST service.
The selected clones are cryopreserved and fully QC-ed before shipment.
Additional characterisation assays (e.g. NGS, SNP, differentiation, pluripotency, genotyping) are also available.