ISSCR standards

ISSCR Standards: Overview

The ISSCR states that its Standards are intended to be both technically and financially feasible for the average research laboratory and, if undertaken, will promote rigor and reproducibility.



Basic characterization to describe cell identity, ensure culture integrity, and promote material safety.



The assessment of the undifferentiated state and pluripotency to appropriately evaluate cells and their developmental potential.


genetic integrity

Genomic characterization to assess genetic integrity and monitor the emergence of cellular changes that could interfere with the interpretation of results or manifest as potentially malignant traits.


model systems

Stem cell-based model systems to improve fidelity and utility of stem cell-derived model systems (organoids, microphysiological systems, engineered cells, etc.) in basic and preclinical research.

The criticality of documentation

In order to support the widespread adoption of the ISSCR Standards, the International Society for Stem Cell Research has helpfully published a practical, easy-to-use Standards Checklist which can be downloaded and which comprises a “fillable checklist pdf”.

Increasingly, Journals are insisting on use of this Checklist in relation to data presented in publications.

Cellected uses this ISSCR Standards Checklist as a default position for its Services – including RIQUEST, RESCUE and Isogenic cell line derivation.

Please contact Cellected if you have any questions around practical and proportionate solutions to preparing appropriate documentation for iPSCs – or other cell lines – which incorporates this ISSCR documentation